Publications

Found 142 results
2012
A. S. Petrov, Bernier, C. R., Hsiao, C., C Okafor, D., Tannenbaum, E., Stern, J., Gaucher, E., Schneider, D., Hud, N. V., Harvey, S. C., and Williams, L. Dean, “RNA-magnesium-protein interactions in large ribosomal subunit.”, J Phys Chem B, vol. 116, no. 28, pp. 8113-20, 2012.
S. Imari Walker, Grover, M. A., and Hud, N. V., “Universal sequence replication, reversible polymerization and early functional biopolymers: a model for the initiation of prebiotic sequence evolution.”, PLoS One, vol. 7, no. 4, p. e34166, 2012.
2011
L. N. Anumukonda, Young, A., Lynn, D. G., Buckley, R., Warrayat, A., Graves, C. L., Bean, H. D., and Hud, N. V., “Adenine Synthesis in a Model Prebiotic Reaction: Connecting Origin of Life Chemistry with Biology.”, J Chem Educ, vol. 88, no. 12, pp. 1698-1701, 2011.
G. T. Lautenslager, Shearman, C. W., Hud, E., and Cohen, M. P., “Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin.”, Metabolism, vol. 60, no. 12, pp. 1683-91, 2011.
R. Buckley, C Enekwa, D., Williams, L. Dean, and Hud, N. V., “Molecular recognition of Watson-Crick-like purine-purine base pairs.”, Chembiochem, vol. 12, no. 14, pp. 2155-8, 2011.
2010
I. Mamajanov, Engelhart, A. E., Bean, H. D., and Hud, N. V., “DNA and RNA in anhydrous media: duplex, triplex, and G-quadruplex secondary structures in a deep eutectic solvent.”, Angew Chem Int Ed Engl, vol. 49, no. 36, pp. 6310-4, 2010.
H. L. Barks, Buckley, R., Grieves, G. A., Di Mauro, E., Hud, N. V., and Orlando, T. M., “Guanine, adenine, and hypoxanthine production in UV-irradiated formamide solutions: relaxation of the requirements for prebiotic purine nucleobase formation.”, ChemBioChem, vol. 11, no. 9, pp. 1240-3, 2010.
E. D. Horowitz, Engelhart, A. E., Chen, M. C., Quarles, K. A., Smith, M. W., Lynn, D. G., and Hud, N. V., “Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world.”, Proc Natl Acad Sci U S A, vol. 107, no. 12, pp. 5288-93, 2010.
A. E. Engelhart and Hud, N. V., “Primitive genetic polymers.”, Cold Spring Harb Perspect Biol, vol. 2, no. 12, p. a002196, 2010.
2009
Y. Sheng, Bean, H. D., Mamajanov, I., Hud, N. V., and Leszczynski, J., “Comprehensive investigation of the energetics of pyrimidine nucleoside formation in a model prebiotic reaction.”, J Am Chem Soc, vol. 131, no. 44, pp. 16088-95, 2009.
A. G. Tsai, Engelhart, A. E., Hatmal, M. 'monM., Houston, S. I., Hud, N. V., Haworth, I. S., and Lieber, M. R., “Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.”, J Biol Chem, vol. 284, no. 11, pp. 7157-64, 2009.
A. E. Engelhart, Morton, T. Hellman, and Hud, N. V., “Evidence of strong hydrogen bonding by 8-aminoguanine.”, Chem Commun (Camb), no. 6, pp. 647-9, 2009.
T. Sarkar, Petrov, A. S., Vitko, J. R., Santai, C. T., Harvey, S. C., Mukerji, I., and Hud, N. V., “Integration host factor (IHF) dictates the structure of polyamine-DNA condensates: implications for the role of IHF in the compaction of bacterial chromatin.”, Biochemistry, vol. 48, no. 4, pp. 667-75, 2009.
N. V. Hud, “Mineral surfaces: a mixed blessing for the RNA world?”, Astrobiology, vol. 9, no. 2, pp. 253-5; discussion 256, 2009.
I. Suk Joung, Cetinkol, O. Persil, Hud, N. V., and Cheatham, T. E., “Molecular dynamics simulations and coupled nucleotide substitution experiments indicate the nature of A{middle dot}A base pairing and a putative structure of the coralyne-induced homo-adenine duplex.”, Nucleic Acids Res, vol. 37, no. 22, pp. 7715-27, 2009.
O. Persil Cetinkol and Hud, N. V., “Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding.”, Nucleic Acids Res, vol. 37, no. 2, pp. 611-21, 2009.
E. D. Horowitz, Lilavivat, S., Holladay, B. W., Germann, M. W., and Hud, N. V., “Solution structure and thermodynamics of 2',5' RNA intercalation.”, J Am Chem Soc, vol. 131, no. 16, pp. 5831-8, 2009.
2008
A. E. Engelhart, Plavec, J., Persil, O., and Hud, N. V., “Metal Ion Interactions with G-Quadruplex Structures”, in Nucleic Acid-Metal Ion Interactions , Cambridge: Royal Society of Chemistry, 2008, pp. 118 - 153.
O. Persil Cetinkol, Engelhart, A. E., Nanjunda, R. K., W Wilson, D., and Hud, N. V., “Submicromolar, selective G-quadruplex ligands from one pot: thermodynamic and structural studies of human telomeric DNA binding by azacyanines.”, ChemBioChem, vol. 9, no. 12, pp. 1889-92, 2008.
2007
N. V. Hud, Jain, S. S., Li, X., and Lynn, D. G., “Addressing the problems of base pairing and strand cyclization in template-directed synthesis: a case for the utility and necessity of 'molecular midwives' and reversible backbone linkages for the origin of proto-RNA.”, Chem Biodivers, vol. 4, no. 4, pp. 768-83, 2007.
T. Sarkar, Vitoc, I., Mukerji, I., and Hud, N. V., “Bacterial protein HU dictates the morphology of DNA condensates produced by crowding agents and polyamines.”, Nucleic Acids Res, vol. 35, no. 3, pp. 951-61, 2007.
N. V. Hud and Morton, T. Hellman, “DFT energy surfaces for aminopurine homodimers and their conjugate acid ions.”, J Phys Chem A, vol. 111, no. 17, pp. 3369-77, 2007.
H. D. Bean, Sheng, Y., Collins, J. P., Anet, F. A. L., Leszczynski, J., and Hud, N. V., “Formation of a beta-pyrimidine nucleoside by a free pyrimidine base and ribose in a plausible prebiotic reaction.”, J Am Chem Soc, vol. 129, no. 31, pp. 9556-7, 2007.
O. Persil and Hud, N. V., “Harnessing DNA intercalation.”, Trends Biotechnol, vol. 25, no. 10, pp. 433-6, 2007.
P. Podbevsek, Hud, N. V., and Plavec, J., “NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution.”, Nucleic Acids Res, vol. 35, no. 8, pp. 2554-63, 2007.

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