Publications

Found 142 results
2022
M. Frenkel-Pinter, Jacobson, K. C., Eskew-Martin, J., Forsythe, J. G., Grover, M. A., Williams, L. Dean, and Hud, N. V., “Differential Oligomerization of Alpha versus Beta Amino Acids and Hydroxy Acids in Abiotic Proto-Peptide Synthesis Reactions”, Life, vol. 12, no. 2, p. 265, 2022.
T. P. Roche, Fialho, D. M., Menor‐Salván, C., Krishnamurthy, R., Schuster, G. B., and Hud, N. V., “A Plausible Prebiotic Path to Nucleosides: Ribosides and Related Aldosides Generated from Ribulose, Fructose, and Similar Abiotic Precursors”, Chemistry – A European Journal, 2022.
G. B. Schuster, Hud, N. V., and Alenaizan, A., “Structural and Thermodynamic Control of Supramolecular Polymers and DNA Assemblies with Cyanuric Acid: Influence of Substituents and Intermolecular Interactions”, The Journal of Physical Chemistry B, vol. 126, no. 50, pp. 10758 - 10767, 2022.
M. Frenkel-Pinter, Bouza, M., Fernández, F. M., Leman, L. J., Williams, L. Dean, Hud, N. V., and Guzman-Martinez, A., “Thioesters provide a plausible prebiotic path to proto-peptidesAbstract”, Nature Communications, vol. 13, no. 1, 2022.
A. Lozoya‐Colinas, Clifton, B. E., Grover, M. A., and Hud, N. V., “Urea and Acetamide Rich Solutions Circumvent the Strand Inhibition Problem to Allow Multiple Rounds of DNA and RNA Copying”, ChemBioChem, vol. 23, no. 1, 2022.
M. C, Frenkel-Pinter, M., Smith, K. H., Rivera-Santana, V. F., Sargon, A. B., Jacobson, K. C., Guzman-Martinez, A., Williams, L. Dean, Leman, L. J., Liotta, C. L., Grover, M. A., and Hud, N. V., “Water-Based Dynamic Depsipeptide Chemistry: Building Block Recycling and Oligomer Distribution Control Using Hydration–Dehydration Cycles”, JACS Au, vol. 2, no. 6, pp. 1395 - 1404, 2022.
2021
D. M. Fialho, Karunakaran, S. C., Greeson, K. W., Martínez, I., Schuster, G. B., Krishnamurthy, R., and Hud, N. V., “Depsipeptide Nucleic Acids: Prebiotic Formation, Oligomerization, and Self-Assembly of a New Proto-Nucleic Acid CandidateDepsipeptide Nucleic Acids: Prebiotic Formation, Oligomerization and Self-Assembly of a New Proto-Nucleic Acid Candidate”, Journal of the American Chemical Society, vol. 143, no. 34, pp. 13525 - 13537, 2021.
N. S. Sahajpal, Mondal, A. K., Ananth, S., Njau, A., Ahluwalia, P., Newnam, G., Lozoya-Colinas, A., Hud, N. V., Kota, V., Ross, T. M., Reid, M. D., Fulzele, S., Chaubey, A., Hegde, M., Rojiani, A. M., and Kolhe, R., “SalivaSTAT: Direct-PCR and Pooling of Saliva Samples Collected in Healthcare and Community Setting for SARS-CoV-2 Mass Surveillance”, Diagnostics, vol. 11, no. 5, p. 904, 2021.
S. Mangalath, Karunakaran, S. C., Newnam, G., Schuster, G. B., and Hud, N. V., “Supramolecular assembly-enabled homochiral polymerization of short (dA)n oligonucleotides”, Chemical Communications, vol. 57, no. 99, pp. 13602 - 13605, 2021.
M. Frenkel-Pinter, Sargon, A. B., Glass, J. B., Hud, N. V., and Williams, L. Dean, “Transition metals enhance prebiotic depsipeptide oligomerization reactions involving histidine”, RSC Advances, vol. 11, no. 6, pp. 3534 - 3538, 2021.
B. A. Anderson, Fauché, K., Karunakaran, S. C., Yerabolu, J. R., Hud, N. V., and Krishnamurthy, R., “The Unexpected Base‐Pairing Behavior of Cyanuric Acid in RNA and Ribose versus Cyanuric Acid Induced Helicene Assembly of Nucleic Acids: Implications for the Pre‐RNA Paradigm”, Chemistry – A European Journal, vol. 27, no. 12, pp. 4033 - 4042, 2021.
M. Frenkel-Pinter, Rajaei, V., Glass, J. B., Hud, N. V., and Williams, L. Dean, “Water and Life: The Medium is the Message”, Journal of Molecular Evolution, vol. 89, no. 1-2, pp. 2 - 11, 2021.
G. B. Schuster, Cafferty, B. J., Karunakaran, S. C., and Hud, N. V., “Water-Soluble Supramolecular Polymers of Paired and Stacked Heterocycles: Assembly, Structure, Properties, and a Possible Path to Pre-RNA”, Journal of the American Chemical Society, vol. 143, no. 25, pp. 9279 - 9296, 2021.
A. Alenaizan, Borca, C. H., Karunakaran, S. C., Kendall, A. K., Stubbs, G., Schuster, G. B., C. Sherrill, D., and Hud, N. V., “X-ray Fiber Diffraction and Computational Analyses of StackeXray Fiber Diffraction and Computational Analyses of Stacked Hexads in Supramolecular Polymers: Insight into Self-Assembly in Water by Prospective Prebiotic Nucleobases”, Journal of the American Chemical Society, vol. 143, no. 16, pp. 6079 - 6094, 2021.
2020
S. J. Mascuch, Fakhretaha-Aval, S., Bowman, J. C., Ma, M. Thu H., Thomas, G., Bommarius, B., Ito, C., Zhao, L., Newnam, G. P., Matange, K. R., Thapa, H. R., Barlow, B., Donegan, R. K., Nguyen, N. A., Saccuzzo, E. G., Obianyor, C. T., Karunakaran, S. C., Pollet, P., Rothschild-Mancinelli, B., Mestre-Fos, S., Guth-Metzler, R., Bryksin, A. V., Petrov, A. S., Hazell, M., Ibberson, C. B., Penev, P. I., Mannino, R. G., Lam, W. A., García, A. J., Kubanek, J. M., Agarwal, V., Hud, N. V., Glass, J. B., Williams, L. Dean, and Lieberman, R. L., “A blueprint for academic labs to produce SARS-CoV-2 RT-qPCR test kits”, Journal of Biological Chemistry, vol. 295, no. 46, pp. 15438-15453, 2020.
C. Obianyor, Newnam, G., Clifton, B., Grover, M., and Hud, N. V., “Comparison of multiple factors that impact the efficiency of non‐enzymatic DNA ligation: Key parameters for maximizing ligation rates and yields with carbodiimide activation”, ChemBioChem, vol. 21, no. 23, pp. 3359-3370, 2020.
M. Frenkel-Pinter, Haynes, J. W., Mohyeldin, A. M., C, M., Sargon, A. B., Petrov, A. S., Krishnamurthy, R., Hud, N. V., Williams, L. Dean, and Leman, L. J., “Mutually stabilizing interactions between proto-peptides and RNA”, Nature Communications, vol. 11, no. 1, 2020.
J. L. Lago, Burcar, B. T., Hud, N. V., Febrian, R., Mehta, C., Bracher, P. J., Atlas, Z. D., and Pasek, M. A., “The Prebiotic Provenance of Semi-Aqueous Solvents”, Origins of Life and Evolution of Biospheres, vol. 50, no. 1-2, pp. 1 - 14, 2020.
D. M. Fialho, Roche, T. P., and Hud, N. V., “Prebiotic Syntheses of Noncanonical Nucleosides and Nucleotides”, Chemical Reviews, vol. 120, no. 11, pp. 4806 - 4830, 2020.
A. Alenaizan, Barnett, J. L., Hud, N. V., C Sherrill, D., and Petrov, A. S., “The proto-Nucleic Acid Builder: a software tool for constructing nucleic acid analogsAbstract”, Nucleic Acids Research, vol. 49, no. 1, pp. 79 - 89, 2020.
S. C. Karunakaran, Cafferty, B. J., Jain, K. S., Schuster, G. B., and Hud, N. V., “Reversible Transformation of a Supramolecular Hydrogel by Redox Switching of Methylene Blue—A Noncovalent Chain Stopper”, ACS Omega, vol. 5, no. 1, pp. 344 - 349, 2020.
2019
N. V. Hud and Fialho, D. M., “RNA nucleosides built in one prebiotic pot”, Science, vol. 366, no. 6461, pp. 32 - 33, 2019.
M. Frenkel-Pinter, Haynes, J. W., C, M., Petrov, A. S., Burcar, B. T., Krishnamurthy, R., Hud, N. V., Leman, L. J., and Williams, L. Dean, “Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions”, Proceedings of the National Academy of Sciences USA, vol. 116, no. 33, pp. 16338 - 16346, 2019.
C. He, Lozoya-Colinas, A., Gállego, I., Grover, M. A., and Hud, N. V., “Solvent viscosity facilitates replication and ribozyme catalysis from an RNA duplex in a model prebiotic process”, Nucleic Acids Research, vol. 47, no. 13, pp. 6569 - 6577, 2019.
S. C. Karunakaran, Cafferty, B. J., Weigert-Muñoz, A., Schuster, G. B., and Hud, N. V., “Spontaneous Symmetry Breaking in the Formation of Supramolecular Polymers: Implications for the Origin of Biological Homochirality”, Angewandte Chemie International Edition, vol. 58, no. 5, pp. 1453 - 1457, 2019.

Pages